Mediastinitis caused by an NDM-1 Escherichia coli in a child with Dacron Sano shunt after pulmonary atresia with ventricular septal defect surgery treated with combination of aztreonam-avibactam.
Vladimir L CousinJordi MiatelloRoberto SierraTornike SologashviliJulie WackerDiego O AndreyArnaud G L'HuillierPublished in: International journal of antimicrobial agents (2024)
Carbapenem-resistant Enterobacterales are being reported increasingly and cause nosocomial infections, which may include postoperative mediastinitis. This paper reports a case of postoperative mediastinitis caused by an Escherichia coli NDM-1 carbapenemase producer in a 13-month-old boy with DiGeorge syndrome. The infection was managed with surgical debridement and antibiotherapy with aztreonam, ceftazidime-avibactam and IV fosfomycin for 6 weeks. The evolution was favourable, without relapse over 10 weeks of follow-up.
Keyphrases
- klebsiella pneumoniae
- escherichia coli
- multidrug resistant
- gram negative
- patients undergoing
- minimally invasive
- pulmonary hypertension
- gestational age
- heart failure
- mental health
- coronary artery bypass
- drug resistant
- biofilm formation
- pulmonary artery
- acinetobacter baumannii
- left ventricular
- case report
- urinary tract infection
- surgical site infection
- atrial fibrillation
- methicillin resistant staphylococcus aureus
- pulmonary arterial hypertension
- percutaneous coronary intervention