A phase I, nonrandomized controlled trial demonstrating the novel technique of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy utilizing warm humidified carbon dioxide insufflation.
Celine GarrettDaniel SteffensNabila AnsariCherry KohPublished in: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland (2021)
WHCO2 in CRS and HIPEC appears to be safe and feasible. An appropriately powered phase II trial will be required to determine if WHCO2 is associated with improved intra- and postoperative outcomes.
Keyphrases
- carbon dioxide
- open label
- minimally invasive
- coronary artery bypass
- patients undergoing
- study protocol
- locally advanced
- surgical site infection
- double blind
- clinical trial
- metastatic renal cell carcinoma
- placebo controlled
- metabolic syndrome
- radiation therapy
- adipose tissue
- skeletal muscle
- insulin resistance
- weight loss