Altered Cytotoxicity Profile of CD8+ T Cells in Ankylosing Spondylitis.
Eric GraceyYuchen YaoZoya QaiyumMelissa LimMichael TangRobert D InmanPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2020)
Our findings indicate that AS patients have an altered cytotoxic T cell profile. These data suggest that CD8+ T cells with a cytotoxic phenotype are recruited to the joints, where they exhibit an activated phenotype. Thus, a central role for CD8+ T cells in AS may have been overlooked and deserves further study.