RNA sequence analysis reveals ITGAL/CD11A as a stromal regulator of murine low-grade glioma growth.

Amanda De Andrade CostaJit ChatterjeeOlivia CobbShilpa SanapalaXiaofan GuoJeffrey R Millman David H Gutmann

Published in: Neuro-oncology (2021)

Collectively, these findings establish ITGAL/CD11A as a critical microglia regulator of LGG biology relevant to future stroma-targeted brain tumor treatment strategies.

Keyphrases

low grade
high grade
transcription factor
nk cells
inflammatory response
bone marrow
current status
cancer therapy
neuropathic pain
spinal cord
spinal cord injury
nucleic acid