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Conservation of the C-type lectin fold for accommodating massive sequence variation in archaeal diversity-generating retroelements.

Sumit HandaBlair G PaulJeffery F MillerDavid L ValentinePartho Ghosh
Published in: BMC structural biology (2016)
Our results have uncovered the widespread conservation of the CLec-fold in viruses, bacteria, and archaea for accommodating massive sequence variation. In addition, to our knowledge, this is the first report of an archaeal CLec-fold protein.
Keyphrases
  • amino acid
  • healthcare
  • protein protein
  • binding protein
  • genetic diversity