Challenges and lessons learned from clinical pharmacogenetic implementation of multiple gene-drug pairs across ambulatory care settings.

Emily J CicaliKristin Wiisanen WeitzelAmanda R ElseyFrank A OrlandoMichelle VinsonScott MosleyD Max SmithRichard DavisLori DrumDavid EstoresJames P FranciosiMelanie Gross HagenGabriel J JerkinsElvira S MercadoJaison NainaparampilAdaixa PadronEric I RosenbergAshleigh WrightSiegfried O SchmidtCarol A MathewsLarisa H CavallariJulie A Johnson

Published in: Genetics in medicine : official journal of the American College of Medical Genetics (2019)

The lessons learned from implementing three gene-drug pairs in ambulatory care settings will help shape future pharmacogenetic clinical trials and clinical implementations.

Keyphrases

quality improvement
healthcare
clinical trial
blood pressure
palliative care
copy number
genome wide
gene expression
study protocol
phase ii