Blood-based screening for HPV-associated cancers.
Dipon DasShun HirayamaLing AyeMichael E BryanSaskia NaegeleBrian ZhaoVasileios EfthymiouJulia MendelAdam S FischLea KröllerBirgitta E MichelsTim WaterboerJeremy D RichmonViktor AdalsteinssonMichael S LawrenceMatthew Gordon CrowsonA John IafrateDaniel L FadenPublished in: medRxiv : the preprint server for health sciences (2024)
We demonstrate accurate blood-based detection of HPV-associated cancers with lead times up to 10 years before clinical cancer diagnosis and in doing so, highlight the enormous potential of ctDNA-based cancer screening.