The effect of metformin treatment on leukocyte telomere length in patients with polycystic ovary syndrome: a prospective case-control study.

Özlem Kayacık Günday Müjgan Özdemir Erdoğan Ayşen Pehlivan Mehmet Yılmazer

Published in: Journal of assisted reproduction and genetics (2022)

Although statistically insignificant, LTL increased after metformin use in PCOS patients, and the mean weight loss reduction was statistically significant. Telomere shortening increased the likelihood of PCOS 0.4 times.

Keyphrases

polycystic ovary syndrome
insulin resistance
weight loss
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
bariatric surgery
peritoneal dialysis
metabolic syndrome
type diabetes
peripheral blood
weight gain
obese patients
glycemic control