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The Expression Profile of MicroRNAs in Small and Large Abdominal Aortic Aneurysms.

Vaclava CernaPavel OstašovPavel PituleJiří MoláčekVladislav TřeškaMartin Pesta
Published in: Cardiology research and practice (2019)
We confirmed some previously identified miRNAs (miR-23/27/24 family, miR-193a, and miR-30) as associated with AAA pathogenesis. We have found other, yet in AAA unidentified miRNAs (miR-203a, miR-3663, miR-365a, and miR-4291) for further analyses, to investigate more closely their possible role in pathogenesis of aneurysms. If their role in AAA development is proved significant in future, they can become potential markers or treatment targets.
Keyphrases
  • cell proliferation
  • long non coding rna
  • long noncoding rna