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Y Chromosome Genes May Play Roles in the Development of Neural Rosettes from Human Embryonic Stem Cells.

Farzaneh KhaniSimin NafianSepideh MollamohammadiShiva NematiBahare ShokoohianSeyedeh-Nafiseh HassaniHossein BaharvandHamid Reza Soleimanpour-LichaeiGhasem Hosseini Salekdeh
Published in: Stem cell reviews and reports (2022)
Our results suggest that the RPS4Y1 gene may play a critical role in neurogenesis. Also, the generated transgenic ESC lines can be widely employed in basic and preclinical studies, such as sexual dimorphism of neural and cardiac functions, the development of cancerous and non-cancerous disease models, and drug screening.
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