Consumption of Ashtanga Ghrita (clarified cow butter added with herb extracts) improves cognitive dysfunction induced by scopolamine in rats via regulation of acetylcholinesterase activity and oxidative stress.
Vineet SharmaZeba FirdausHimanshu RaiPrasanta Kumar NayakTryambak Deo SinghDev Nath Singh GautamPublished in: Drug metabolism and personalized therapy (2021)
This study demonstrates that AG protects the brain from SCP-induced dementia by promoting brain antioxidant activity and thus could be a promising drug for the treatment of neurodegenerative disease.
Keyphrases
- oxidative stress
- diabetic rats
- resting state
- white matter
- functional connectivity
- mild cognitive impairment
- drug induced
- cerebral ischemia
- high glucose
- cognitive impairment
- quantum dots
- emergency department
- multiple sclerosis
- induced apoptosis
- ischemia reperfusion injury
- highly efficient
- signaling pathway
- adverse drug
- brain injury
- replacement therapy