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Cold-induced dishabituation in rodents exposed to recurrent hypoglycaemia.

Keeran VicknesonJessica BlackburnJennifer R GallagherMark L EvansBastiaan E De GalanUlrik Pedersen-BjergaardBernard ThorensAlison D McNeillyRory J McCrimmon
Published in: Diabetologia (2021)
Non-diabetic rodents exhibit two cardinal features of habituation, namely stimulus generalisation and dishabituation. These findings provide further support for the hypothesis that suppressed counterregulatory responses following exposure to recurrent hypoglycaemia in diabetes result from habituation.
Keyphrases
  • type diabetes
  • glycemic control
  • cardiovascular disease
  • high glucose
  • diabetic rats
  • insulin resistance
  • oxidative stress
  • wound healing