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Optimizing DCD Liver Grafts With Prolonged Warm Ischemic Time Using Stabilized Plasmin in a Static Cold Storage Orthotopic Rat Liver Transplant Model.

Riley KahanNader AbrahamMin ZhangValery NovokhatnyIsaac AlderetePaul CrayFengming ChenQimeng GaoGreta CywinskaRyan NeillKentaro NakataAhmed HassanCaroline RushJude PenaflorJustin J PollaraMatthew G HartwigBenjamin HughesAndrew S Barbas
Published in: Transplantation direct (2024)
The present study demonstrates that plasmin improves survival and may reduce thrombotic burden in DCD liver grafts with prolonged warm ischemic injury, meriting further study.
Keyphrases
  • oxidative stress
  • risk factors
  • cerebral ischemia
  • blood brain barrier
  • free survival