Design, Synthesis and Evaluation of the Biological Activities of Some New Carbohydrazide and Urea Derivatives.

Fatih TokRecep IlhanSelin GünalPetek Ballar-KirmizibayrakBedia Koçyiğit-Kaymakçioğlu

Published in: Turkish journal of pharmaceutical sciences (2018)

Our data indicate that compounds 3a-d are more selective to cancer cells compared with nontumoral fibroblasts; however, these compounds are not more potent on HR defective cells with BRCA mutants.

Keyphrases

induced apoptosis
cell cycle arrest
electronic health record
big data
oxidative stress
signaling pathway
cell death
machine learning
cell proliferation
pi k akt
wild type
artificial intelligence
data analysis
breast cancer risk