Repository Describing the Anatomical, Physiological, and Biological Changes in an Obese Population to Inform Physiologically Based Pharmacokinetic Models.

Mattia BertonSara BettonteFelix StaderManuel BattegayCatia Marzolini

Published in: Clinical pharmacokinetics (2022)

using continuous physiological changes and their variability for each system parameter. It is a tool that can be implemented in PBPK models to simulate drug pharmacokinetics in obese individuals.

Keyphrases

adipose tissue
weight loss
metabolic syndrome
type diabetes
obese patients
bariatric surgery
drug induced
adverse drug