Platelet-derived growth factor signaling in pericytes promotes hypothalamic inflammation and obesity.

Akira OkekawaTsutomu WadaYasuhiro OnogiYuki TakedaYuichiro MiyazawaMasakiyo SasaharaHiroshi TsunekiToshiyasu Sasaoka

Published in: Molecular medicine (Cambridge, Mass.) (2024)

PDGF receptor β signaling in hypothalamic pericytes promotes polarization of macrophages by changing their secretome and contributes to the progression of obesity.

Keyphrases

growth factor
insulin resistance
metabolic syndrome
weight loss
high fat diet induced
type diabetes
weight gain
oxidative stress
adipose tissue
vascular smooth muscle cells
body mass index