Long-term exposure to air pollution and trajectories of cognitive decline among older adults.
Erin R KulickGregory A WelleniusAmelia K BoehmeNina R JoyceNicole SchupfJoel Daniel KaufmanRichard MayeuxRalph L SaccoJennifer J ManlyMitchell S V ElkindPublished in: Neurology (2020)
WHICAP participants living in areas with higher levels of ambient air pollutants have lower cognitive scores at enrollment and more rapid rates of cognitive decline over time. In NOMAS, a smaller cohort with fewer repeat measurements, we found no statistically significant associations. These results add to the evidence regarding the adverse effect of air pollution on cognitive aging and brain health.
Keyphrases
- cognitive decline
- air pollution
- mild cognitive impairment
- particulate matter
- lung function
- healthcare
- public health
- resting state
- white matter
- mental health
- depressive symptoms
- heavy metals
- health insurance
- health information
- risk assessment
- functional connectivity
- climate change
- multiple sclerosis
- chronic obstructive pulmonary disease
- brain injury
- affordable care act
- health promotion
- electronic health record
- blood brain barrier