Hyperglycemia disrupted the integrity of the blood-brain barrier following diffuse axonal injury through the sEH/NF-κB pathway.

Xing WeiZhiguo XingTingqin HuangMing ZhangJinning SongYonglin Zhao

Published in: Immunity, inflammation and disease (2024)

sEH was involved in mediating axonal injury induced by hyperglycemia after DAI by disrupting BBB integrity through inducing inflammation via the NF-κB pathway.

Keyphrases

oxidative stress
signaling pathway
spinal cord injury
lps induced
diabetic rats
pi k akt
nuclear factor
blood brain barrier
low grade
optic nerve
immune response
resting state