Risk factors for mixed chimerism in children with hemophagocytic lymphohistiocytosis after reduced toxicity conditioning.
Katharina WustrauJohann GreilKarl-Walter SykoraMichael H AlbertBirgit BurkhardtPeter LangRoland MeiselWilhelm WössmannRita BeierAnsgar SchulzPeter BaderMartin ChadaJörn-Sven KühlPaul-Gerhardt SchlegelCarsten SpeckmannBernd GruhnMarkus G SeidelAngela WawerAnn-Kathrin OzgaGritta JankaStephan EhlIngo MüllerKai LehmbergPublished in: Pediatric blood & cancer (2020)
The use of an HLA-matched donor is the most important factor to avoid substantial recipient chimerism following treosulfan -or melphalan-based conditioning in primary HLH.