Gallstones, Body Mass Index, C-reactive Protein and Gallbladder Cancer - Mendelian Randomization Analysis of Chilean and European Genotype Data.
Carol Barahona PonceDominique SchererRegina BrinsterFelix BoekstegersKatherine MarcelainValentina GárateBettina MüllerGonzalo de ToroJavier RetamalesOlga BarajasMonica AhumadaErik MoralesArmando RojasVerónica SanhuezaDenisse LoaderMaría Teresa RiveraLorena GutiérrezGiuliano BernalAlejandro OrtegaDomingo MontalvoSergio PortiñoMaria Enriqueta BertránFernando GablerLoreto SpencerJordi OlloquequiChristine FischerMazda JenabKrasimira AleksandrovaVerena KatzkeElisabete WeiderpassCatalina BonetTahereh MoradiKrista FischerWillem BossersHermann BrennerKristian HveemNiina EklundUwe VölkerMelanie WaldenbergerMacarena Fuentes GuajardoRolando Gonzalez-JoseGabriel BedoyaMaria C BortoliniSamuel CanizalesCarla GalloAndres Ruiz LinaresFrancisco RothhammerJusto Lorenzo BermejoPublished in: Hepatology (Baltimore, Md.) (2020)
Two risk factors considered in the current Chilean programme for GBC prevention are causally linked to GBC risk: gallstones and BMI. For Europeans, BMI showed a causal effect on gallstone risk, which was itself causally linked to GBC risk.
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