SN1-Type Alkylation of N-Heteroaromatics with Alcohols.
Mingyan XiaoDidi RenLubin XuShuai-Shuai LiLiping YuJian XiaoPublished in: Organic letters (2018)
The organocatalytic alkylation of 2-methyl-N-heteroaromatics with alcohols has been achieved via SN1-type C(sp3)-H functionalization, providing a green and efficient synthesis of indole and ferrocene-functionalized N-heteroaromatics in high yields.