Carbohydrate/DBU Cocatalyzed Alkene Diboration: Mechanistic Insight Provides Enhanced Catalytic Efficiency and Substrate Scope.

Lu YanYan MengFredrik HaeffnerRobert M LeonMichael P CrockettJames P Morken

Published in: Journal of the American Chemical Society (2018)

A mechanistic investigation of the carbohydrate/DBU cocatalyzed enantioselective diboration of alkenes is presented. These studies provide an understanding of the origin of stereoselectivity and also reveal a strategy for enhancing reactivity and broadening the substrate scope.

Keyphrases

genome wide
structural basis
amino acid
single cell
case control
gene expression