Mucinous adenocarcinoma of the colon and rectum: A genomic analysis.

Ian S ReynoldsEmer O'ConnellMichael FichtnerDeborah A McNamaraElaine W KayJochen H M PrehnSimon J FurneyJohn P Burke

Published in: Journal of surgical oncology (2019)

Mucinous CRC has some distinct genomic aberrations when compared with non-mucinous adenocarcinoma, many of which are driven by the increased frequency of MSI-H tumors. These genomic aberrations may play an important part in the difference seen in response to treatment and prognosis in mucinous adenocarcinoma.

Keyphrases

low grade
copy number
squamous cell carcinoma
locally advanced
high grade