The Link Between Periodontal Inflammation and Obesity.
Misaki IwashitaMasato HayashiYuki NishimuraAkiko YamashitaPublished in: Current oral health reports (2021)
Loss of adipose tissue homeostasis induces increase and activation of immune cells in adipose tissue, leading to impaired immune function in obesity. Various cytokines and chemokines are secreted from obese adipose tissue and promote inflammatory signaling. Some of these signaling pathways have been suggested to affect energy regulation. The combination of obesity and periodontitis amplifies inflammation to levels that affect the whole body through the adipose tissue. Obesity, in turn, accelerates the exacerbation of periodontitis.
Keyphrases
- adipose tissue
- insulin resistance
- metabolic syndrome
- weight loss
- high fat diet induced
- high fat diet
- type diabetes
- oxidative stress
- weight gain
- skeletal muscle
- bariatric surgery
- chronic obstructive pulmonary disease
- sensitive detection
- epithelial mesenchymal transition
- cell proliferation
- body mass index
- quantum dots
- pi k akt
- respiratory failure
- living cells