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DNA image cytometry parameters to identify high-grade cervical lesions.

Ane Francyne CostaAdriane PogereAna Paula Beltrame Farina PasinatoAlexandre Sherlley Casimiro OnofreFabiana Botelho de Miranda Onofre
Published in: Cytopathology : official journal of the British Society for Clinical Cytology (2022)
For prognostic purposes, 1 cell with 9cEE, 45 cells with 4cEE and aneuploid stemline are the best parameters with which to categorise an abnormal DNA-ICM result, followed by 50 cells with 2.5cEE and 4 cells with 5cEE. For screening purposes, 10 cells with 2.5cEE, 10 cells with 4cEE, and 2 cells with 5cEE are suitable parameters with which to categorise a suspicious DNA-ICM result.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • endoplasmic reticulum stress
  • cell death
  • stem cells
  • oxidative stress
  • single molecule
  • single cell
  • machine learning
  • cell free
  • cell proliferation
  • mesenchymal stem cells