Identification of potential therapeutic targets for nonischemic cardiomyopathy in European ancestry: an integrated multiomics analysis.

Kaijia Shi Xu ChenYangyang ZhaoPeihu LiJinxuan ChaiJianmin QiuZhihua Shen Junli Guo Wei Jie

Published in: Cardiovascular diabetology (2024)

Based on European Ancestry Cohort, this study reveals that LILRA5 and NELL1 are potential therapeutic targets for NISCM, with LILRA5 showing particularly promising prospects in diabetic cardiomyopathy. Several small molecules interact with LILRA5, implying potential clinical implication.

Keyphrases

heart failure
type diabetes
current status
atrial fibrillation
cardiac resynchronization therapy
bioinformatics analysis