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Impact of Baseline Clinical Variables on SGLT2i's Antiproteinuric Effect in Diabetic Kidney Disease.

Irene CapelliDanilo RibichiniMichele ProvenzanoDaniele VetranoValeria AielloGiuseppe CiancioloValentina VicennatiAlessandro TomassettiGinevra MoschioneSabrina BertiUberto PagottoGaetano La Manna
Published in: Life (Basel, Switzerland) (2023)
In this real-life experience, following the administration of SGLT2i, a reduction of more than 30% in proteinuria was observed in more than half of the patients, and these patients had a significantly higher baseline proteinuria value. Variables such as eGFR and BMI are variables that, considered in conjunction with proteinuria, can help predict treatment response before therapy initiation. Different phenotypes of diabetic kidney disease may have an impact on the antiproteinuric response.
Keyphrases
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • type diabetes
  • chronic kidney disease
  • prognostic factors
  • stem cells
  • body mass index
  • patient reported outcomes
  • wound healing