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Autophagy induction by thiostrepton improves the efficacy of immunogenic chemotherapy.

Yan WangWei XieJuliette HumeauGuo ChenPeng LiuJonathan PolZhen ZhangOliver KeppGuido Kroemer
Published in: Journal for immunotherapy of cancer (2020)
Altogether, these results indicate that thiostrepton can be advantageously combined with chemotherapy to enhance anticancer immunogenicity.
Keyphrases
  • locally advanced
  • cell death
  • endoplasmic reticulum stress
  • signaling pathway
  • oxidative stress
  • squamous cell carcinoma
  • rectal cancer