Relying only on symptoms to consider a sleep study in PH patients is a missed opportunity to detect OSA, which, if present and not treated, can worsen outcomes. The potential prognostic role of sleep study metrics such as oxygen desaturation index (ODI), hypoxic burden (HB) and ventilatory burden (VB) in OSA should be studied in prospective trials to identify patients at risk for PH. AHI alone has not provided clarity. In those with PH, we should consider replacing ambulatory overnight pulse oximetry (OPO) with home sleep studies (HST). In PH patients, mild OSA should be sufficient to consider PAP therapy.
Keyphrases
- obstructive sleep apnea
- end stage renal disease
- newly diagnosed
- ejection fraction
- pulmonary hypertension
- chronic kidney disease
- physical activity
- positive airway pressure
- patient reported outcomes
- skeletal muscle
- mesenchymal stem cells
- risk factors
- climate change
- pulmonary arterial hypertension
- weight loss
- solid state