The Kidney Contains Ontogenetically Distinct Dendritic Cell and Macrophage Subtypes throughout Development That Differ in Their Inflammatory Properties.

Natallia SaleiStephan RambichlerJohanna SalvermoserNikos E PapaioannouRonja SchuchertDalia PakalniškytėNa LiJulian A MarschnerJulia LichtnekertChristopher StremmelFilippo M CernilogarMelanie SalvermoserBarbara WalzogTobias StraubGunnar SchottaHans-Johachim AndersChristian SchulzBarbara U Schraml

Published in: Journal of the American Society of Nephrology : JASN (2020)

Distinct developmental programs contribute to renal DC and macrophage populations throughout life, which could have important implications for therapies targeting these cells.

Keyphrases

dendritic cells
induced apoptosis
adipose tissue
cell cycle arrest
regulatory t cells
oxidative stress
public health
immune response
cancer therapy
endoplasmic reticulum stress
cell death
signaling pathway
cell proliferation
drug delivery
genetic diversity