Login / Signup

MitoBlue as a tool to analyze the mitochondria-lysosome communication.

Mateo I SánchezYolanda VidaEzequiel Pérez-InestrosaJosé L MascareñasM Eugenio VázquezAyumu SugiuraJacobo Gómez
Published in: Scientific reports (2020)
MitoBlue is a fluorescent bisamidine that can be used to easily monitor the changes in mitochondrial degradation processes in different cells and cellular conditions. MitoBlue staining pattern is exceptional among mitochondrial dyes and recombinant fluorescent probes, allowing the dynamic study of mitochondrial recycling in a variety of situations in living cells. MitoBlue is a unique tool for the study of these processes that will allow the detailed characterization of communication between mitochondria and lysosomes.
Keyphrases
  • living cells
  • fluorescent probe
  • oxidative stress
  • single molecule
  • induced apoptosis
  • small molecule
  • cell proliferation
  • endoplasmic reticulum
  • flow cytometry