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Restoration of T Cell function in multi-drug resistant bacterial sepsis after interleukin-7, anti-PD-L1, and OX-40 administration.

Lukose K ThampyKenneth E RemyAndrew H WaltonZachery HongKelilah LiuRebecca LiuVictoria YiCarey-Ann D BurnhamRichard S Hotchkiss
Published in: PloS one (2018)
Immuno-adjuvant therapy reversed T cell dysfunction, a key pathophysiological mechanism in septic patients with MDR bacteria.
Keyphrases
  • drug resistant
  • multidrug resistant
  • acute kidney injury
  • acinetobacter baumannii
  • intensive care unit
  • septic shock
  • oxidative stress
  • low density lipoprotein