Prevention and Management of Osteoradionecrosis in Patients With Head and Neck Cancer Treated With Radiation Therapy: ISOO-MASCC-ASCO Guideline.
Douglas E PetersonShlomo A KoyfmanYarom NoamCharlotte Duch LynggaardNofisat IsmailaLone E FornerClifton David FullerYvonne M MoweryBarbara A MurphyErin E Watson EDavid H YangIvan AlajbegPaolo BossiMichael FritzNeal D FutranDaphna Y GelblumEdward KingSalvatore RuggieroDerek K SmithAlessandro VillaJonn S WuDeborah SaundersPublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)
Due to limitations of available evidence, the guideline relied on informal consensus for some recommendations. Recommendations that were deemed evidence-based with strong evidence by the Expert Panel were those pertaining to best practices in prevention of ORN and surgical management. No recommendation was possible for the utilization of leukocyte- and platelet-rich fibrin or photobiomodulation for prevention of ORN. The use of hyperbaric oxygen in prevention and management of ORN remains largely unjustified, with limited evidence to support its practice.Additional information is available at www.asco.org/head-neck-cancer-guidelines.