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Genetic Risk of Second Primary Cancer in Breast Cancer Survivors: The Multiethnic Cohort Study.

Fei ChenSungshim L ParkLynne R WilkensPeggy WanSteven N HartChunling HuSiddhartha YadavFergus J CouchDavid V ContiAdam J de SmithChristopher A Haiman
Published in: Cancer research (2022)
This multiethnic study links germline pathogenic variants in BRCA1, BRCA2, and ERCC2 to the development of second primary cancer in breast cancer survivors, providing biological insights and biomarkers to guide patient monitoring.
Keyphrases
  • papillary thyroid
  • squamous cell
  • dna repair
  • copy number
  • case report
  • lymph node metastasis
  • squamous cell carcinoma
  • genome wide
  • childhood cancer
  • dna damage
  • breast cancer risk