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White matter hyperintensity, neurofilament light chain, and cognitive decline.

Anisa DhanaCharles DeCarliKlodian DhanaPankaja DesaiRobert S WilsonDenis A EvansKumar B Rajan
Published in: Annals of clinical and translational neurology (2022)
While both biomarkers, WMH and NfL, were similarly associated with the annual rate of cognitive decline, our study suggests that they provide different underlying mechanisms affecting cognition.
Keyphrases
  • cognitive decline
  • mild cognitive impairment
  • white matter
  • multiple sclerosis
  • cerebrospinal fluid