Resection of NAFLD/NASH-related Hepatocellular Carcinoma (HCC): Clinical Features and Outcomes Compared with HCC Due to Other Etiologies.
Surendra Pal ChaudharyStephanie ReyesMatthew L ChaseAparna GovindanLei ZhaoJay LutherIrun BhanEmily BetheaJoseph W FransesElizabeth Paige WalshLeigh Anne DagefordShoko KimuraNahel EliasHeidi YehJames MarkmanAdel BozorgzadehKenneth TanabeCristina FerroneAndrew X ZhuKarin AnderssonMichael ThiimOnofrio Antonio CatalanoAvinash KambadakoneParsia A VagefiMotaz QadanDaniel PrattNikroo HashemiKathleen E CoreyJoseph MisdrajiLipika GoyalJeffrey W ClarkPublished in: The oncologist (2023)
Patients with NAFLD/NASH-related HCC more commonly lacked liver fibrosis and presented with larger HCCs compared with patients with HCC from other etiologies. No differences were seen in rates of other high-risk features or survival. With the caveat of sample size and retrospective analysis, this supports a similar decision-making approach regarding surgical resection for NAFLD/NASH and other etiology-related HCCs.