Risk-reducing surgery in unaffected individuals receiving cancer genetic testing in an integrated health care system.
Sarah A KnerrBoya GuoKathleen F MittendorfHeather Spencer FeigelsonMarian J GilmoreGail P JarvikTia L KauffmanErin KeastFrances L LynchKristin R MuessigSonia OkuyamaDavid L VeenstraJamilyn M ZeppKatrina A B GoddardBeth DevinePublished in: Cancer (2022)
Uptake of risk-reducing surgery following usual care genetic testing appears to be lower than in studies that actively recruit high-risk patients and provide testing and follow-up care in specialized settings. Factors in addition to genetic test results and NCCN guidelines motivate prophylactic surgery use and deserve further study.
Keyphrases
- minimally invasive
- coronary artery bypass
- palliative care
- healthcare
- end stage renal disease
- surgical site infection
- newly diagnosed
- quality improvement
- papillary thyroid
- prognostic factors
- gene expression
- peritoneal dialysis
- clinical practice
- affordable care act
- chronic pain
- copy number
- dna methylation
- atrial fibrillation