Effects of pathogen reduction technology and storage duration on the ability of cryoprecipitate to rescue induced coagulopathies in vitro.
Kimberly A ThomasSusan M SheaPhilip C SpinellaPublished in: Transfusion (2021)
PR-Cryo FC provides similar and/or improved hemostatic rescue compared to FibCon in dilutional coagulopathies, and this rescue ability is stable over 10 days of storage. In hemorrhaging patients, where every minute delay is associated with a 5% increase in mortality, the immediate availability of PR-Cryo FC has the potential to improve outcomes.
Keyphrases
- end stage renal disease
- high resolution
- ejection fraction
- newly diagnosed
- chronic kidney disease
- prognostic factors
- peritoneal dialysis
- electron microscopy
- type diabetes
- risk factors
- cardiovascular events
- cardiovascular disease
- diabetic rats
- high glucose
- adipose tissue
- patient reported outcomes
- coronary artery disease
- metabolic syndrome
- risk assessment