Effect of Metabolic Traits on the Risk of Cirrhosis and Hepatocellular Cancer in Nonalcoholic Fatty Liver Disease.

Fasiha Kanwal Jennifer R Kramer Liang LiJianliang DaiYamini NatarajanXian YuSteven M Asch Hashem E El-Serag

Published in: Hepatology (Baltimore, Md.) (2020)

Each additional metabolic trait increased the risk of cirrhosis and HCC in patients with NAFLD. Diabetes conferred the highest risk of progression to HCC. Patients with diabetes and coexisting hypertension and obesity may be important targets for secondary prevention.

Keyphrases

type diabetes
genome wide
papillary thyroid
blood pressure
metabolic syndrome
insulin resistance
cardiovascular disease
weight loss
squamous cell
glycemic control
weight gain
high fat diet induced
gene expression
dna methylation
squamous cell carcinoma
adipose tissue
young adults
childhood cancer