[Improving the quality of hematological studies using sigmametry.]
O V PetrovaG R ShabanovaO I MuryginaE V PanovaD M NikulinaPublished in: Klinicheskaia laboratornaia diagnostika (2019)
The purpose - evaluated the quality of the implementation of hematology studies using sigmametry. Studies were perfomed at the Federal state budgetary establishment "Federal center cardiovascular surgery". The data were collected in the period for 2017 y. The following hematology parameters were monitored daily: white cells, red blood cell, platelet, hemoglobin. For conducting laboratory quality control we used certified three-level (Level 1 (low) , Level 2 (normal)and Level 3 (High)) control material "CBC-XE Hematology control" ("R and D Systems", USA). The study of blood hematology parameters was carried out on an automatic hematology analyzer "Sysmex XT- 2000i" and "Sysmex XT- 1800i" ("Sysmex Corporation", Japan). Sigmametry values were calculated the CV (coefficient of variation), the systematic error (Bias) and the total allowable analytical error (TE max). On the analyzer «Sysmex XT- 2000i» sigma values for platelet were between 3 and 4. For white blood cells, red blood cells, hemoglobin the value of the sigma was greater than 4. On the analyzer «Sysmex XT- 1800i» for platelet, white blood cells, red blood cells, hemoglobin the value of the sigma was greater than 4. Based on the results obtained, we drew conclusions on the choice of control material and the frequency of the internal laboratory quality control. The introduction of sigmametry in the daily activities of clinic laboratory will improve the quality of the determination of platelet, which requires further observation.
Keyphrases
- red blood cell
- quality control
- induced apoptosis
- cell cycle arrest
- physical activity
- quality improvement
- endoplasmic reticulum stress
- cell death
- magnetic resonance imaging
- signaling pathway
- case control
- deep learning
- cell proliferation
- high resolution
- solid phase extraction
- percutaneous coronary intervention
- atrial fibrillation
- coronary artery bypass