Association of kidney function with SGLT2 inhibitor discontinuation among United States Veterans.
Jesse C IkemeErin MaddenJulio Alejandro Lamprea-MontealegreChi D ChuMichael G ShlipakIan Ellis McCoyMichelle M EstrellaPublished in: Clinical journal of the American Society of Nephrology : CJASN (2024)
A substantial proportion of patients experience SGLT2i discontinuation within a year of initiation. Persons with lower eGFR had higher discontinuation rates; however, this trend attenuated over time. Additional studies identifying determining factors of discontinuation are needed to fully realize the benefits of SGLT2i.