Fluoxetine Protects Retinal Ischemic Damage in Mice.
Giovanni Luca RomanoLucia GozzoOriana Maria MaurelSerena Di MartinoValentina RioloVincenzo MicaleFilippo DragoClaudio BucoloPublished in: Pharmaceutics (2023)
Topical treatment with FLX was effective in counteracting the damage of RGCs and preserving retinal function. Moreover, FLX treatment attenuates the production of pro-inflammatory molecules elicited by retinal I/R damage. Further studies need to be performed to support the use of FLX as neuroprotective agent in retinal degenerative diseases.