Myelin-associated proteins are potential diagnostic markers in patients with primary brain tumour.
Olga Martyna Koper-LenkiewiczAnna J MilewskaJoanna KamińskaKarol SawickiRobert ChrzanowskiJustyna DorfJoanna ReszećMarzena TylickaEwa MatuszczakJoanna Matowicka-KarnaZenon MariakMariusz W MuchaRobert PawlakVioletta Dymicka-PiekarskaPublished in: Annals of medicine (2021)
Our results indicated the potential usefulness of CSF Nogo-A and serum MAG evaluation as circulating biomarkers of primary brain tumours. Because blood is relatively easy to obtain, future research should be conducted to explicitly indicate the value of serum MAG concentration evaluation as a brain tumour biomarker.Key messagesMyelin-associated proteins may be circulating brain tumour biomarkers.Nogo-A and MAG proteins seem to be the most useful in brain tumour diagnosis.Decreased CSF Nogo-A concentration is an adverse prognostic factor for patients' survival.