Tract-Specific Spinal Cord Diffusion Tensor Imaging in Friedreich's Ataxia.

Ana Luisa C C HernandezThiago Junqueira Ribeiro de RezendeAlberto R M MartinezMariana R de BritoMarcondes Cavalcante de França Junior

Published in: Movement disorders : official journal of the Movement Disorder Society (2021)

DTI uncovered abnormalities in SC WM tracts, which correlated with clinical features in FRDA. CSA and CST FA in C2 correlated best with disease severity, whereas DC FA showed the largest effect size to differentiate patients and healthy controls. SC WM microstructure is a potential neuroimaging biomarker to be explored in the disease. © 2021 International Parkinson and Movement Disorder Society.

Keyphrases

spinal cord
end stage renal disease
white matter
ejection fraction
newly diagnosed
prognostic factors
dendritic cells
spinal cord injury
neuropathic pain
patient reported outcomes
risk assessment
immune response