Commentary: Reply to 'Transgender and mental health' by Philip Graham.

The letter to the editor from Philip Graham regarding the manuscript 'Early adolescent gender diversity and mental health in the Adolescent Brain Cognitive Development study' (Potter et al., 2021) raises several points that highlight the complexity of the conversation around gender development in youth. While there is an agreement between the original manuscript and much of the letter, some of the issues raised warrant further discussion and clarification.