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Prediction of the prognosis of advanced hepatocellular carcinoma by TERT promoter mutations in circulating tumor DNA.

Mami HiraiHideaki KinugasaKazuhiro NousoShumpei YamamotoHiroyuki TerasawaYuma OnishiAtsushi OyamaTakuya AdachiNozomu WadaMasahiro SakataTetsuya YasunakaHideki OnishiHidenori ShirahaAkinobu TakakiHiroyuki Okada
Published in: Journal of gastroenterology and hepatology (2020)
TERT promoter mutations in ctDNA were associated with short survival and could be a valuable biomarker for predicting the prognosis of patients with advanced HCC.
Keyphrases
  • circulating tumor
  • dna methylation
  • cell free
  • circulating tumor cells
  • transcription factor
  • gene expression
  • free survival
  • single molecule