Postoperative Analgesia in Neonates and Infants Using Epidural Chloroprocaine and Clonidine.
Anna GibbsStephani S KimGrant HeydingerGiorgio VenezianoJoseph Drew TobiasPublished in: Journal of pain research (2020)
With the recognized limitations of a retrospective study, these preliminary data demonstrate the safety of adding clonidine to an epidural infusion of 2-chloroprocaine in neonates and infants less than 12 months of age. Future studies are needed to determine its analgesic efficacy compared to 2-chloroprocaine alone and the optimal clonidine concentration for postoperative epidural infusions.