Depression, obesity and their comorbidity during pregnancy: effects on the offspring's mental and physical health.
Nadia CattaneKatri RäikkönenRoberta AnnivernoClaudio MencacciMarco Andrea RivaCarmine Maria ParianteAnnamaria CattaneoPublished in: Molecular psychiatry (2020)
Depression and obesity represent two of the most common complications during pregnancy and are associated with severe health risks for both the mother and the child. Although several studies have analysed the individual effects of depression or obesity on the mothers and their children, the effects associated with the co-occurrence of both disorders have so far been poorly investigated. The relationship between depression and obesity is very complex and it is still unclear whether maternal depression leads to obesity or vice versa. It is well known that the intrauterine environment plays an important role in mediating the effects of both depression and obesity in the mother on the fetal programming, increasing the child's risk to develop negative outcomes.
Keyphrases
- insulin resistance
- metabolic syndrome
- weight loss
- depressive symptoms
- high fat diet induced
- type diabetes
- weight gain
- mental health
- sleep quality
- healthcare
- public health
- adipose tissue
- young adults
- risk factors
- physical activity
- skeletal muscle
- birth weight
- pregnant women
- risk assessment
- early onset
- health information
- glycemic control
- single molecule