[Astrocytoma with 1p19q codeletion].

Marina Ryzhova S A Galstyan L V Shishkina T N Panina E I Voronina E N Telysheva Anastasiya O Kotelnikova D V Starovoitov E G Shaikhaev G P Snigireva R V Sycheva Sh U KadyrovA R AdaevD I Pitskhelauri E S Kudieva Olga Zheludkova Andrey V Golanov

Published in: Arkhiv patologii (2023)

Using the example of a recurrent tumor with a 10-year follow-up, the authors show that mutation of the IDH1/2 genes in astrocytomas is not always an early event in the pathogenesis of glioma, that in rare cases a 1p19q codeletion can be found in astrocytomas, and that IDH-mutant tumors can occur in childhood.

Keyphrases

wild type
low grade
genome wide
bioinformatics analysis
early life
genome wide identification
childhood cancer
gene expression
transcription factor