Therapeutic plasma exchange decreases plasma anti-SARS-CoV-2 spike IgG without increasing the proximate incidence of COVID-19.
Jensyn Cone SullivanSteven E ConklinStephanie ConradCoby HorowitzMark DiethelmRaymond ComenzoPublished in: Journal of clinical apheresis (2023)
TPE significantly reduced SAb levels, a marker of SARS-CoV-2 immunity, but did not appear to provoke increased incidence of COVID-19 infections. Further investigation of the kinetics of TPE-mediated SAb decrease and post-TPE recovery are warranted.